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KMID : 0383820100690060469
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Tuberculosis and Respiratory Diseases
2010 Volume.69 No. 6 p.469 ~ p.473
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A Case of Pneumonia with Septic Shock Due to Nocardia farcinia in Liver Transplant Patient
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Lee Su-Hwan
Park Byung-Hoon
Son Ji-Young
Jung Ji-Ye
Kim Eun-Young
Lim Ju-Eun
Lee Ji-Hoon
Hyun Shin-Young
Lee Sang-Hoon
Lee Sang-Kook
Kim Song-Yee
Lee Kyung-Jong
Kang Young-Ae
Kim Young-Sam
Kim Se-Kyu
Chang Joon
Seo You-Kyung
Lee Kyung-Won
Park Moo-Suk
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Abstract
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Nocardia farcinia, an aerobic, gram-positive bacilli actinomycetes of the genus Nocardia, is an uncommon pathogen found in humans. The most common Nocardia infection sites are the lung, central nervous system, and skin. Even though hematogenous dissemination can occur, isolation of the organism from blood cultures is very rare. We report a case of Nocardia infection that was isolated on blood cultures. A 59-year-old male with a medical history that includes a liver transplantation 6-years prior due to hepatocellular carcinoma secondary to chronic hepatitis B, developed pneumonia and was transferred to Severance Hospital. At the time of admission, the patient’s initial exam showed hypothermia, tachypnea, and hypotension. His chest radiograph showed severe pneumonia and a large abscess on left upper lobe. Under the presumptive diagnosis of bacterial pneumonia or other opportunistic infection, we started broad spectrum antibiotics. However, he developed Nocardia sepsis, rapidly deteriorated, and subsequently died.
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KEYWORD
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Nocardia, Pneumonia, Shock, Sepsis, Liver Transplantation
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